Renowned researcher interviewed by CheckRare about largest Parkinson’s study ever attempted.
Dr. Steven Cummings highlights role of PCM Trials certified mobile research nurses in making possible large-scale home-based clinical trial.
Imagine wanting to conduct a large clinical trial involving complicated protocols that typically would be done only at a clinical site. Further imagine that most of the patients you’d need to enroll would be elderly and have mobility challenges making travel to a site difficult, if not impossible.
It might seem like such a study would be impossible given those constraints but, in fact, it’s underway. The TOPAZ study is being conducted to determine whether a drug used to treat osteoporosis will reduce bone fractures in Parkinson’s disease patients. The home-based clinical trial is the largest of its kind for Parkinson’s patients and is being managed by a team of researchers including the Executive Director of the San Francisco Coordinating Center, Dr. Steven Cummings, an internationally recognized expert on the epidemiology of osteoporosis, women’s health, and aging.
In an interview with CheckRare, a digital learning platform focused on rare diseases, Dr. Cummings discusses how PCM Trials certified mobile research nurses are making the TOPAZ study possible. He shares details about the specific protocols carried out by the nurses from renal function tests to oral exams to infusions of the IV study drug and placebos. You can download a case study on the TOPAZ trial here. PCM Trials thanks CheckRare for making the interview available.
Dr. Steven Cummings of the San Francisco Coordinating Center on the essential role of PCM Trial’s certified mobile research nurses in serving more than 500 patients involved in the TOPAZ study in more than 40 states:
“And the good thing is, as we find a person who’s eligible, PCM Trials is able to find a nurse. South Dakota? No problem. Iowa? No problem. Sometimes it requires a nurse to go stay overnight in a hotel and then go see the patient, but they are very flexible, adaptable, and that’s what has made this big trial, the largest ever done in Parkinson’s, feasible. A feasible thing to design. A feasible thing to get funded. And a feasible thing to do.”
Learn how PCM Trials is leading the way with in-home clinical trials:
Source statement: Interview with Dr. Steven Cummings courtesy of CheckRare